Stability of selected CV-A13.67900/MAD4 and CV-B4/MAD4 recombinants upon serial passaging.

a The recombinant group is indicated in brackets. The name of a recombinant includes the type (e.g. CV-A13.67900/MAD4) and class (A) followed by the laboratory number (64).
b The 5’ UTR domain in which the recombination site is located is indicated in brackets. For example, (dIII-dIV) designates the linker sequence between domains dIII and dIV.
c In these particular homologous recombinants (which contain neither an insertion nor a deletion) a few partner nt were replaced with different nt at the junction (sequence indicated).
d The length of insertions (+) and deletions (-) is given. For insertions, the duplicated IRES domains are indicated in square brackets. Homologous recombinant sites are shown (H).
e Number of passages. The status of the resulting recombinant is indicated following passaging. Homologous: loss of insertion. Parental: recombination site unchanged, conservation of the parental virus sequences. Mixture: mixture of parental and homologous recombinants.
Stability of selected CV-A13.67900/MAD4 and CV-B4/MAD4 recombinants upon serial passaging.