Genome-wide analysis of skin biopsies during the mucocutaneous HSV-2 reactivation. Homo sapiens

Analysis of host response at the gene expression level during the genital HSV-2 reactivation. We would like to get a comprehensive overview on host gene expression and correlate them with the infiltrated immune cell types during HSV-2 reactivation. The hypothesis is that HSV-2 may evade some aspects of host immune response during the recurrent infection. Overall design: Total RNA obtained from lesion and post healing skin biopsies as compared to contralateral control skin biopsies