five

Fly gut transcriptome for neural control of microbiota

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP010460
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Drosophila melanogaster NP3253 is a Gal4 enhancer trap strain. When some neurons are artificially inactivated using this strain (NP3253>Kir2.1), fly becomes susceptible to bacteria oral infection. NP3253>Kir fly is also sensitive to microbiota. To address this mechanism, RNA-seq of fly gut was performed, when the neurons were inactivated (NP3253>Kir2.1) or were normal (NP3253>GFP) in conventionally reared or germ-free condition.
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2023-08-30
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