Abcb4
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ENCODES a protein that exhibits ATPase-coupled transmembrane transporter activity (ortholog); ceramide floppase activity (ortholog); phosphatidylcholine floppase activity (ortholog); INVOLVED IN response to glucocorticoid; response to xenobiotic stimulus; bile acid secretion (ortholog); PARTICIPATES IN multidrug resistance protein mediated transport pathway; bile acid transport pathway; ASSOCIATED WITH cholestasis; Experimental Diabetes Mellitus; Animal Disease Models (ortholog); FOUND IN apical plasma membrane; Golgi membrane; cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1,9-dideoxyforskolin; 1-naphthyl isothiocyanate
编码一种表现出ATP酶偶联的跨膜转运蛋白活性(同源物);鞘氨醇翻转酶活性(同源物);磷脂酰胆碱翻转酶活性(同源物);参与对糖皮质激素的反应;对外来刺激的反应;胆汁酸分泌(同源物);参与多药耐药蛋白介导的转运途径;胆汁酸转运途径;与胆汁淤积、实验性糖尿病、动物疾病模型(同源物)相关;存在于顶侧质膜、高尔基膜、细胞质(同源物);与(+)-五味子素B、1,9-二脱氧 forskolin、1-萘基异硫氰酸酯相互作用。
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