Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea

Protein Data Bank Japan2024-01-31 更新2026-03-21 收录

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Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea Descriptor: COENZYME A, MANGANESE (II) ION, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, ... Authors: Maveyraud, L, Carivenc, C, Blanger, C, Mourey, L. Deposit date: 2020-12-02 Release date: 2021-11-10 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11, 2021

脓肿分枝杆菌（Mycobacterium abscessus）来源的4'-磷酸泛酰巯基乙胺转移酶（4'-phosphopantetheinyl transferase）PptAb与辅酶A（Coenzyme A）及N-(2,6-二乙基苯基)-N'-(N-乙基氨基甲脒基)尿素的复合物结构。描述：辅酶A、二价锰离子（MANGANESE (II) ION）、N-(2,6-二乙基苯基)-N'-(N-乙基氨基甲脒基)尿素……作者：Maveyraud L、Carivenc C、Blanger C、Mourey L。存档日期：2020-12-02；发布日期：2021-11-10；最后修改日期：2024-01-31。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.4 Å）。引用文献：《脒基脲与羟基嘧啶硫酮类化合物对磷酸泛酰巯基乙胺转移酶的结合与抑制作用》，Sci Rep，11卷，2021年

创建时间：

2020-12-02