Overview of NLR family members according to their domain organization.

Protein name and synonyms (new synonyms in bold), accession number, and chromosomal location according to http://www.genenames.org/genefamily/nlr.php followed by domains as defined by FFAS. CARD, caspase activation and recruitment domain; PYD, pyrin; NACHT, domain present in NAIP, CIITA, HET-E, TP-1; NALP, NACHT-LRR-PYD-containing protein; WH, winged helix domain; SH, superhelical domain, LRR, leucine-rich repeats.