Multimodal decoding of human liver regeneration [st_human]
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE223559
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资源简介:
Using snRNA-seq combined with spatial profiling of healthy and ALF explant human livers, we uncover a novel migratory hepatocyte subpopulation. We discover a corollary subpopulation in a mouse model of APAP-induced liver regeration, and demonstrate that this subpopulation meidates wound closure following liver injury. Spatial transcriptomics was performed on human liver explants (n=3 healthy, n=3 APAP, n=2 NonAE)
创建时间:
2024-06-25



