Description of 127 shared-types (SITs; n = 364 isolates, 2–56 isolates per cluster) and corresponding spoligotyping families/subfamilies starting from a total of 409 M. tuberculosis complex strains isolated from Swedish patients born before 1945.

A total of 104 SITs containing 332 isolates matched a preexisting shared type in the SITVIT2 database, whereas 23 SITs (n = 32 isolates) were newly-created either within the present study or after a match with an orphan in the database.*SIT followed by an asterisk indicates “newly created shared-type” (n = 24 containing 34 isolates) due to two or more strains belonging to an identical new pattern within this study or after a match with an orphan in the database. SIT designations followed by number of strains: 3168* this study n = 3, PER n = 1; 3169* this study n = 2, USA n = 1; 3170* this study n = 3, SWE n = 1; 3171* this study n = 1, BRA n = 1; 3172* this study n = 1, VEN n = 1; 3173* this study n = 2, POL n = 1; 3174* this study n = 2; 3175 this study n = 1, USA n = 1; 3176* this study n = 1, ZAF n = 1; 3177* this study n = 1, GLP n = 1; 3178* this study n = 1, ALB n = 1; 3179* this study n = 2, FXX n = 2; 3180* this study n = 2, USA n = 1; 3181* this study n = 1, USA n = 1; 3182* this study n = 1, AUS n = 1; 3183* this study n = 1, FXX n = 1, ALB n = 1; 3184* this study n = 1, SWE n = 1; 3185* this study n = 2; 3186* this study n = 1, SWE n = 1; 3187* this study n = 1, SWE n = 1; 3188* this study n = 1, BEL n = 1; 3189* this study n = 1, DEU n = 1; 3190* this study n = 1, DEU n = 1; 3191* this study n = 1, SWE n = 1; 3199* this study n = 1, CHN n = 1, JPN n = 1; 3276* this study n = 1, COL n = 1, ITA n = 1.**Spoligotype family designations according to SITVIT2 using revised SpolDB4 rules; “Unknown” designates patterns with signatures that do not belong to any of the major clades described in the database.***Clustered strains correspond to a similar spoligotype pattern shared by two or more strains “within this study”; as opposed to unique strains harboring a spoligotype pattern that does not match with another strain from this study. Unique strains matching a preexisting pattern in the SITVIT2 database are classified as SITs, whereas in case of no match, they are designated as “orphan”.