Replication Data for: Maintenance of high temporal Plasmodium falciparum genetic diversity in Kilifi, Kenya, despite a reduction in community malaria transmission from 2007 to 2018

This is a replication dataset for the submitted manuscript title: \"Maintenance of high temporal Plasmodium falciparum genetic diversity in Kilifi, Kenya, despite a reduction in community malaria transmission from 2007 to 2018.\" The project describes the genetic diversity and complexity of asymptomatic Plasmodium falciparum infections in Kilifi from 2007 - 2018. It also describes the genetic diversity and COI of follow-up febrile malaria infections and reports that asymptomatic infections have a high genetic diversity despite a reduction in malaria transmission in the region. Blood samples and corresponding metadata were collected from children aged (0-15) years with asymptomatic and follow-up febrile malaria episodes. The samples were genotyped using capillary electrophresis based on the merozoite surface protein 2 (msp2) gene. Metadata from each participant included age and parasitemia (based on microscopy results). The genotypes data include the fragment sizes (labelled as genotypes) corresponding to each successfully identified clone based on capillary electrophoresis.The number of genotypes per participants constitute the complexity of infections otherwise known as COI.本数据集为对应投稿手稿的复现数据集，手稿标题为《2007至2018年肯尼亚基利菲地区社区疟疾传播减弱背景下仍维持高水平恶性疟原虫（Plasmodium falciparum）时间遗传多样性》。本项目针对2007-2018年基利菲地区无症状恶性疟原虫感染的遗传多样性与感染复杂度展开分析；同时解析了后续随访发热性疟疾感染的遗传多样性及感染复杂度（Complexity of Infection, COI），并证实尽管该区域疟疾传播水平有所下降，无症状感染仍保持较高的遗传多样性。研究采集了0-15岁儿童的血液样本及对应元数据（metadata），样本涵盖无症状感染病例与后续发热性疟疾发作病例。所有样本均以裂殖子表面蛋白2（merozoite surface protein 2, msp2）基因为靶点，采用毛细管电泳（capillary electrophoresis）完成基因分型。每名受试者的元数据包含年龄与寄生虫血症水平（基于显微镜检测结果）。基因型数据包含经毛细管电泳成功鉴定的每个克隆对应的片段长度（标记为基因型）。每名受试者携带的基因型总数即为感染复杂度（COI）。