The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide.

The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide. Descriptor: 4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ... Authors: Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R. Deposit date: 2018-07-17 Release date: 2018-12-19 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem, 163, 2018

人类碳酸酐酶VII与4-[(4-氟苯基)甲基]-1-哌嗪基]苯磺酰胺复合物的晶体结构。描述符：4-[4-[(4-氟苯基)甲基]哌嗪-1-基]羰基苯磺酰胺、碳酸酐酶7、甘油（GLYCEROL）等。作者：Buemi, M.R.、Di Fiore, A.、De Luca, L.、Ferro, S.、Mancuso, F.、Monti, S.M.、Buonanno, M.、Angeli, A.、Russo, E.、De Sarro, G.、Supuran, C.T.、De Simone, G.、Gitto, R.。沉积日期：2018-07-17；发布日期：2018-12-19；最后修改日期：2024-10-09。实验方法：X射线衍射（1.7 Å）。引用文献：《含4-(环烷基氨基-1-羰基)苯磺酰胺基团的强效人类碳酸酐酶抑制剂的结构特性探究》，《欧洲医药化学杂志》，163卷，2018年。