Transcriptomics profiling at norvancomycin producing strains
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP256068
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资源简介：
Norvancomycin has been widely used in clinic to against Gram-positive bacteria, especially MRSA (Methicillin-resistant Staphylococcus aureus) and MRSE (methicillin-resistant Staphylococcus epidermidis) in China. Amycolatopsis orientalis NCPC 2-48, a high yield strain derived from Amycolatopsis orientalis CPCC200066, has been used for industrial large-scale production of the vital antibiotic norvancomycin by the North China Pharmaceutical Company. Here we sequenced and compared the transcriptomes of CPCC200066 and NCPC 2-48, to identify high yield mechanism potentially involved in the norvancomycin biosynthetic pathway.
创建时间：
2020-12-31
