Crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor
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Crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor Descriptor: DUAL SPECIFICITY PROTEIN KINASE CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate Authors: Pike, A.C.W, Bullock, A.N, Fedorov, O, Pilka, E.S, Ugochukwu, E, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Huber, K, Bracher, F, Knapp, S. Deposit date: 2007-08-31 Release date: 2007-10-09 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Specific Clk Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing. Chem.Biol, 18, 2011
双磷酸化人源CLK1与新型取代吲哚类抑制剂复合物的晶体结构
描述：双特异性蛋白激酶CLK1，乙基3-[(E)-2-氨基-1-氰基乙烯基]-6,7-二氯-1-甲基-1H-吲哚-2-羧酸酯
作者：Pike, A.C.W、Bullock, A.N、Fedorov, O、Pilka, E.S、Ugochukwu, E、von Delft, F、Edwards, A、Arrowsmith, C.H、Weigelt, J、Sundstrom, M、Huber, K、Bracher, F、Knapp, S.
存入日期：2007-08-31
发布日期：2007-10-09
最后修改日期：2024-11-13
实验方法：X射线衍射（1.8 Å）
引用文献：用于调控可变剪接的新型化学骨架特异性Clk抑制剂，Chem.Biol，第18卷，2011年
创建时间：
2007-08-31
