Transcriptomic analysis of engineered myometrial tissues with varied tissue architecture and matrix rigidity. Transcriptomic analysis of engineered myometrial tissues with varied tissue architecture and matrix rigidity

We report the use of RNA-seq for transcriptional analysis of engineered myometrial tissues cultured on hydrogels with varied matrix rigidity and tissue alignment. Overall design: mRNA profiles of engineered myometrial tissues on representative healthy (13 kPa - aligned) and fibrotic (90 kPa - isotropic) substrates