Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to pyridin-benzenesulfonamide inhibitor

Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to pyridin-benzenesulfonamide inhibitor Descriptor: 4-[6-amino-5-(3,5-difluoro-4-hydroxyphenyl)pyridin-3-yl]benzene-1-sulfonamide, SULFATE ION, Serine/threonine-protein kinase VRK2 Authors: dos Reis, C.V, Chiodi, C.G, de Souza, G.P, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Counago, R.M, Massirer, K.B, Elkins, J.M, Arruda, P, Edwards, A.M, Structural Genomics Consortium (SGC) Deposit date: 2018-12-11 Release date: 2019-01-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to pyridin-benzenesulfonamide inhibitor To Be Published

人类痘病毒相关激酶2（VRK-2）结合吡啶-苯磺酰胺类抑制剂的晶体结构
描述项：该复合物包含抑制剂4-[6-氨基-5-(3,5-二氟-4-羟基苯基)吡啶-3-基]苯-1-磺酰胺、硫酸根离子以及丝氨酸/苏氨酸蛋白激酶VRK2
作者：dos Reis, C.V、Chiodi, C.G、de Souza, G.P、Guimaraes, C、Mascarello, A、Gama, F、Ferreira, M、Counago, R.M、Massirer, K.B、Elkins, J.M、Arruda, P、Edwards, A.M、结构基因组学联盟（Structural Genomics Consortium, SGC）
沉积日期：2018-12-11
发布日期：2019-01-16
最后修改日期：2023-10-11
实验方法：X射线衍射法（分辨率2.45埃）
引用文献：《结合吡啶-苯磺酰胺类抑制剂的人类痘病毒相关激酶2（VRK-2）晶体结构》待发表