NIDDK Central Repository

In 2003, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at NIH established Data, Biosample, and Genetic Repositories to increase the impact of current and previously funded NIDDK studies by making their data and biospecimens available to the broader scientific community. These Repositories enable scientists not involved in the original study to test new hypotheses without any new data or biospecimen collection, and they provide the opportunity to pool data across several studies to increase the power of statistical analyses. In addition, most NIDDK-funded studies are collecting genetic biospecimens and carrying out high-throughput genotyping making it possible for other scientists to use Repository resources to match genotypes to phenotypes and to perform informative genetic analyses.

2003年，美国国立卫生研究院（NIH）下属的国家糖尿病与消化系统及肾脏疾病研究所（NIDDK）建立了数据、生物样本和遗传资源库，旨在通过向更广泛的科学界提供其数据与生物样本，增强当前及以往资助的NIDDK研究的影响力。这些资源库使得未参与原始研究的科学家能够无需收集新数据或新生物样本，即测试新的假设，并提供了跨多研究数据整合以增强统计分析功效的机会。此外，大多数由NIDDK资助的研究正在收集遗传生物样本并执行高通量基因分型，使得其他科学家能够利用资源库资源将基因型与表型相匹配，并执行富有信息性的遗传分析。