Epigenetic alterations are one of the key hallmarks of aging. Emerging evidence in model organisms, senescent cell cultures and limitedly, murine, and human tissue samples suggest local effects impact
Published studies in RAW264.7 cell line and mouse bone marrow macrophages (BMMs) confirm the expression pattern for 17 of the 97 miRNAs regulated during the course of osteoclastogenesis [8], [16]. Cha
To define Atoh1 secretory signature, transcriptional profiling of secretory cells was performed. The expression profile of Atoh1+ cells from Atoh1(WT)CreERT2 R26RtdTom mice was determined by comparing
