Regioselective (Diacetoxyiodo)benzene-Promoted Halocyclization of Unfunctionalized Olefins
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https://figshare.com/articles/dataset/Regioselective_Diacetoxyiodo_benzene_Promoted_Halocyclization_of_Unfunctionalized_Olefins/2237578
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资源简介：
A metal-free
method for intramolecular halocyclization of unfunctionalized
olefins was detailed. (Diacetoxyiodo)benzene (PIDA) was very effective
for haloamidation, haloetherification, and halolactonization of unfunctionalized
olefins. In the presence of 1.1 equiv of PIDA and suitable halogen
sources, a variety of unfunctionalized olefins could be converted
to the corresponding 1,2-bifunctional cyclic skeletons in good to
excellent isolated yields, and key intermediates for biologically
interesting compounds could be obtained in high yields under mild
conditions via nucleophilic substitution of the thus obtained halocyclization
products.
创建时间：
2014-11-07
