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Crystal structure of monkeypox virus poxin in complex with the STING agonist MD1203

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Protein Data Bank Japan2024-04-17 更新2026-06-30 收录
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https://pdbj.org/mine/summary/8orv
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Crystal structure of monkeypox virus poxin in complex with the STING agonist MD1203 Descriptor: 9-[(1~{S},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{R})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one, MPXVgp165 Authors: Duchoslav, V, Klima, M, Boura, E. Deposit date: 2023-04-17 Release date: 2023-12-20 Last modified: 2024-04-17 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function. Structure, 32, 2024
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2023-04-17
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