Structure of dengue virus protease with an allosteric Inhibitor that blocks replication
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Structure of dengue virus protease with an allosteric Inhibitor that blocks replication Descriptor: 5-[4-(aminomethyl)phenyl]-6-[4-(furan-3-yl)phenyl]-N-[(piperidin-4-yl)methyl]pyrazin-2-amine, FLAVIVIRUS_NS2B/Peptidase S7 Authors: Lin, Y.-L, Hua, Y, Nie, S, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. Deposit date: 2018-10-03 Release date: 2019-05-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3 Å) Cite: Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J.Am.Chem.Soc., 141, 2019
结合阻断病毒复制的变构抑制剂的登革病毒蛋白酶结构
描述物:5-[4-(氨基甲基)苯基]-6-[4-(呋喃-3-基)苯基]-N-[(哌啶-4-基)甲基]吡嗪-2-胺,黄病毒NS2B/肽酶S7(FLAVIVIRUS_NS2B/Peptidase S7)
作者:Lin, Y.-L、Hua, Y、Nie, S、Wu, J、Wu, F、Huo, T、Yao, Y、Song, Y
提交日期:2018-10-03
发布日期:2019-05-15
最后修改日期:2023-10-11
实验方法:X射线衍射(3 Å)
引用文献:《黄病毒NS2B-NS3蛋白酶变构抑制剂的发现、X射线晶体学与抗病毒活性》,刊载于《美国化学会志》(J.Am.Chem.Soc.)2019年第141卷
创建时间:
2018-10-03



