Base-Promoted Tandem Synthesis of 2‑Azaaryl Tetrahydroquinolines
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https://figshare.com/articles/dataset/Base-Promoted_Tandem_Synthesis_of_2_Azaaryl_Tetrahydroquinolines/14049533
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资源简介：
A novel method to synthesize 2-azaaryl
tetrahydroquinolines by
the base-promoted tandem reaction of azaaryl methyl amines and styrene
derivatives is reported (over 30 examples, yields up to 95%). Mechanistic
probe experiments demonstrate that the deprotonation of the benzylic
C–H bond and the addition to the styrene vinyl group proceeds
via the SNAr mechanism.
创建时间：
2021-02-17
