GWAS on affect and cognitive performance in the Lifelines Cohort

The following files contain GWAS summary statistic results which were conducted using data from the Lifelines Cohort Study (https://www.lifelines-biobank.com/) [genome build GRCh37]:

QC_METAGWAS_LL_COGSTATE_IDENTIFY_RT_SD1.txt.gz
QC_METAGWAS_LL_PANAS_NEG_SD1.txt.gz
QC_METAGWAS_LL_COGSTATE_OCL_ACC_SD1.txt.gz
QC_METAGWAS_LL_PANAS_POS_SD1.txt.gz
QC_METAGWAS_LL_COGSTATE_ONEBACK_ACC_SD1.txt.gz
QC_METAGWAS_LL_RFFT_SD1.txt.gz

An accompanying file contains the md5sum of each GWAS summary statistic file (md5sum_affect_cognition_gwas.txt). For details on each phenotype, participant criteria, maximum sample size, and covariates included in each GWAS, please see the published paper.

Data Access Conditions
Access to these GWAS summary statistics ("these data") are provided via the University of Bristol Research Data Repository under restricted access conditions.

The conditions below are adapted from the Psychiatric Genetics Consortium (PGC) data access terms and reflect community standards for the responsible use of GWAS summary statistics. Access is granted on the understanding that you and your collaborators ("Investigators") are expected to adhere to the following conditions:

Investigators acknowledge that these data are provided on an “as-is” basis, without warranty of any type, expressed or implied, including but not limited to any warranty as to their performance, merchantability, or fitness for any particular purpose.
Investigators will not cross-post these data or make them available elsewhere - the University of Bristol data repository is the definitive source for these data.
Investigators will never attempt to identify any participant who contributed to these data.
Investigators will use these data solely for non-commercial, non-profit scientific research purposes.
Investigators are responsible for ensuring that their use of these data is always in compliance with all local, state, national, and institutional regulations/policies regarding human subjects and genetics research.
Investigators must not use these data to develop any type of risk or predictive test for an unborn individual.
For any risk or predictive test for a child or adult, investigators must acknowledge that this is an experimental use of these data and that essentially all cognitive and psychiatric phenotypes have important non-genetic etiological components.
Investigators must not use the data for projects that may lead to the stigmatization of individuals or groups.
Investigators will appropriately cite the corresponding publication in any presentations, publications, or communications arising from use of these data.

Header key for all files:
All headers are produced from GWAS Inspector (https://pmc.ncbi.nlm.nih.gov/articles/PMC8034536/), and include the following columns:
CHR: Chromosome
MARKER: Variant identifier/rsid
POSITION: Base pair location
EFFECT_ALL: Effect allele
OTHER_ALL: Other allele
STDERR: Standard error
PVALUE: P-value
EFF_ALL_FREQ: Effect allele frequency
N_TOTAL: N
EFFECT: Beta

Contact and Information
Analyst: Chloe Slaney (https://orcid.org/0000-0003-0463-5516)
Principal Investigators: Prof. Golam Khandaker (https://orcid.org/0000-0002-4935-9220) and Prof. Catharina Hartman (https://orcid.org/0000-0002-8094-8859)