Dataset from The Surfactant Positive Airway Pressure and Pulse Oximetry Trial in Extremely Low Birth Weight Infants

This�2x2 factorial designed randomized clinical trial�compared the use of continuous positive airway pressure initiated at�birth�to the administration of surfactant within 1 hour of�birth�for premature infants�born�at 24 to 27 weeks gestation. In addition, these infants within 2 hours of�birth, had a special pulse oximeter placed to continuously monitor their oxygen saturation in two different target ranges (85-89% or 91-95%). This�study�helped determine whether or not these two management strategies affect survival without bronchopulmonary dysplasia (also called chronic lung disease) and survival without severe retinopathy of prematurity (an eye disorder that can lead to blindness).