Data for: Sublethal effects of dermal exposure to poly- and perfluoroalkyl substances on post-metamorphic amphibians

<p align="left">Studies of poly- and perfluoroalkyl substances (PFAS) toxicity on amphibians, especially post metamorphosis, are limited. We examined effects of dermal PFAS exposure (30 d) on survival and growth of juvenile American toads (<em>Anaxyrus americanus</em>), eastern tiger salamanders (<em>Ambystoma tigrinum</em>) and northern leopard frogs (<em>Rana pipiens</em>). Exposures included perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS) and 6:2 fluorotelomer sulfonate (6:2 FTS) at 0, 80, 800, or 8000 ppb on a moss dry weight basis. Exposure to PFAS influenced final snout-vent length (SVL) and scaled mass index (SMI), a measure of relative body condition. Observed effects depended on species and chemical, but not concentration. Anurans exposed to PFOS, PFHxS (frogs only), and 6:2 FTS reduced SVL versus controls, while salamanders exposed to 6:2 FTS increased SVL. Frogs exposed to PFHxS and 6:2 FTS, and toads exposed to PFOS had increased SMI compared to controls, salamanders did not demonstrate effects. Concentrations of 6:2 FTS in substrate decreased substantially by 30 d, likely driven by microbial action. PFOS had notable biota-sediment accumulation factors, but still < 1. While a no-observable-effect concentration could not generally be determined, the lowest observable effect concentration was 50 - 120 ppb. Survival was not affected. Our work demonstrates that PFAS bioaccumulation from dermal exposures and sublethal effects are dependent on species, chemical, and focal trait. </p>