Demographic Characteristics and Prior Histories of Trial Subjects.

Age denoted in years. IPF Dx denotes when the original IPF diagnosis was established in these subjects, prior to their admission for acute exacerbations. AE = acute exacerbation; UIP = usual interstitial pneumonia.[1] Subjects were not listed for lung transplantation due to advanced age (Subjects #1,2,4–6,8,11), irreparable coronary artery disease (#3), or being too acutely ill to undergo the extensive necessary pre-transplantation evaluations (#7,#9). The AE-IPF in all subjects was rapidly progressive, with daily or near daily increases of hypoxemia and dyspnea. None had infections, congestive heart failure, or other causes of pulmonary dysfunction aside from the AE-IPF (2).Demographic Characteristics and Prior Histories of Trial Subjects.