Mutational study of the EGFR feedback monomerization at the PLCγ binding sites.

a F stands for the phosphodeficient mutation (phenylalanine substitution).b The strength of negative feedback scaled from as strong as for the EGFRwt (+ +) to none (—).c, d Minimum (Dmin) and maximum (Dmax) level of the diffusion coefficient.e The diffusion coefficient averaged over the whole measurement time after EGF addition (Davg).f Not determinable.Mutational study of the EGFR feedback monomerization at the PLCγ binding sites.

a F代表磷缺失突变（苯丙氨酸替代）。b 负反馈强度从与EGFRwt (+ +)一样强烈至无（—）。c, d 扩散系数的最小（Dmin）和最大（Dmax）水平。e EGF添加后整个测量时间内扩散系数的平均值（Davg）。f 不可测定。对EGFR反馈单体化在PLCγ结合位点的突变研究。