This data contains fitness values for PPAT protein mutants described in:Plesa C, Sidore AM, Lubock N, Zhang D, Kosuri S. Multiplexed Gene Synthesis in Emulsions for Exploring Protein Functional Landsc
Examine the effects of mutations in two paralogous type-1 myosins in the model organism Saccharomyces cerevisiae on the evolution of the endocytosis protein interaction network.
Underlined characters represent mutated amino acids that led to the elimination of allosteric regulation without loss of enzyme activity. Residues with conservation scores<0.5 are highlighted with bol