Principal components of embryonic stem cell pluripotency
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Principal components of embryonic stem cell pluripotency
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2013-03-14
相关数据集
Enhancing the Potency of Mouse Embryonic Stem Cells [BS-Seq]. Mus musculus
Mouse naïve pluripotent stem cells (ESC) can contribute to all embryonic tissues and the germline, but rarely to the extra-embryonic tissues in chimeric embryos. Here we describe a novel advanced plur
NIAID Data Ecosystem80
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq
All mammals develop from embryonic founder cells with the ability to generate all of the differentiated cells that constitute the organism. Capture of stem cells with such developmental potential in v
NIAID Data Ecosystem40
Network characterization linc1393 in the maintenance of pluripotency provides the principles for lncRNA targets prediction. Mus musculus
In this study, we demonstrate that a nuclear lncRNA linc1393 maintains mouse ESC pluripotency by recruiting SET1A near its binding sites, to establish H3K4me3 status and activate the expression of spe
NIAID Data Ecosystem10
Acetylated histone H3K56 interacts with Oct4 to promote mouse embryonic stem cell pluripotency
The presence of acetylated histone H3K56 in human embryonic stem cells (ESCs) correlates positively with the binding of Nanog, Sox2 and Oct4 (NSO) transcription factors at their target gene promoters.
NIAID Data Ecosystem50
RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells (RNAi)
We performed an integrated analysis of RNA and proteins at the transition between naïve ES cells and cells primed to differentiate. During this transition, mRNAs coding for chromatin regulators were s
NIAID Data Ecosystem30
