Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4 + 2] Cycloadditions Catalyzed by Amidine Derivatives
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https://figshare.com/articles/dataset/Asymmetric_Synthesis_of_i_cis_i_-3_4-Dihydrocoumarins_via_4_2_Cycloadditions_Catalyzed_by_Amidine_Derivatives/4956377
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A highly efficient chiral amidine derivative-catalyzed tandem Michael addition/lactonization of carboxylic acids and o-quinone methides (o-QMs) has been developed that enables the asymmetric synthesis of cis-3,4-dihydrocoumarins bearing contiguous tertiary stereogenic centers in high yields with excellent stereoselectivities.
创建时间:
2017-05-01



