Protection of mice immunized with a low dose of VLPs.
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Mice were intramuscularly immunized with 0.1 µg of VLPs once or twice, and were challenged with a lethal dose of A/California/04/2009 (10 LD50) (n = 6) day 10 post immunization. Mice were observed daily to monitor changes in body weight and to record mortality (25% loss in body weight as the IACUC endpoint).
创建时间:
2015-12-02



