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Create a compound motif of GATA1 and TAL1 in the non coding region of the HBZ gene

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NIAID Data Ecosystem2026-05-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP550735
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资源简介:
The introduction of the complex binding site of GATA1 and TAL1 in -216 ~ -278 bp upstream of HBZ gene can effectively activate zeta-globin.Transplantation of edited CD34+HSPCs cells into NCG-X mice resulted in effective implantation and activation of zeta-globin in vivo.
创建时间:
2026-01-01
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