Impact of the treatments on whole blood platelet aggregation (aggregometry AUC).
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Treatments were: PBS (n = 6), empty microparticles (n = 8), free GSNO at 7.5mg/k g(n = 5) or 30 mg/kg (n = 5), in situ implants loaded with 7.5 ± 0.8 mg/kg (n = 7) or 32.1 ± 4.3 mg/kg (n = 10) of GSNO and in situ microparticles loaded with 7.9 ± 0.6 mg/kg (n = 7) or 31.4 ± 3.6 mg/kg (n = 10) of GSNO. The red vertical dashed lines represent the time of injection. †: p vs. 1 h following substance administration within the same group (one-way ANOVA; post-hoc Bonferroni test).
创建时间：
2016-02-23
