Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide

Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide Descriptor: H2CasMab-1 VH(S112C),SARAH, H2CasMab-1 VL,SARAH(S37C), H2CasMab-1 epitope peptide Authors: Arimori, T, Takagi, J. Deposit date: 2023-07-03 Release date: 2024-03-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies. Structure, 32, 2024与表位肽结合的癌症特异性抗HER2抗体H2Mab-214的晶体结构 描述项：H2CasMab-1 重链可变区（VH）(S112C)、SARAH、H2CasMab-1 轻链可变区（VL）、SARAH(S37C)、H2CasMab-1表位肽 作者：Arimori T、Takagi J 存库日期：2023-07-03 发布日期：2024-03-13 最后修改日期：2024-11-13 实验方法：X射线衍射（1.75 Å） 引用文献：癌细胞表面表达的局部错误折叠HER2是开发癌症特异性抗体的极具潜力的靶点。《Structure》，第32卷，2024年