Data set of Trigeminal neuralgia study in Ethiopian

This is a data set was from a facility based cross sectional study aimed to assess clinical characteristics, treatment, and associated factors in Trigeminal neuralgia (TN) patients in a Addis Ababa, Ethiopia. We analyzed total of sixty-one patients (n=61) from four health facilities in Addis Ababa Ethiopia. All patients with confirmed TN who presented to the four health facilities during the six month study period were included in the study. All the patients were interviewed and examined by board certified neurologist. Structured questionnaires were utilized to extract demographic, clinical, and imaging data from all the patients after informed consent was obtained. Descriptive analysis, Chi-square, student t-test, binary and multivariate analysis were used to describe the results. The data set contains the following data: demographic, clinical characteristics related to trigeminal neuralgia such as classification, duration of illness, involved side, involved nerve branch, history of dental extraction, quality of pain, triggering factors, triggering zone, treatment satisfaction, type of medications, and comorbidity. Additional data related to associated autonomic dysfunction, family history of trigeminal neuralgia, symptoms changes with seasonal changes, history of surgical procedures, and brain imaging findings. These data represent a data obtained by cross sectional at neurological out patients clinics. Therefore, it should be analyzed and interpreted accordingly. We decided to share these data with other colleagues because, this is the first study about Trigeminal neuralgia in Ethiopia, if not the sub-Saharan Africa (SSA). Such paucity of clinical information from the sub Saharan Africa regarding trigeminal neuralgia resulted in wide spread miss management, delayed diagnosis, and sub-optimal treatment of patients with trigeminal neuralgia in Africa. Thus far, this is the first cohort of trigeminal neuralgia patients in Ethiopia. Therefore, we decided to characterize their clinical features and simultaneously opt to determine the cause of delayed diagnosis and treatment satisfaction of our patients. One of the most important finding from our study was the high prevalence of dental extraction (41%) among TN patients in Ethiopia. This information is vital to us in such as way close to half of our patients with trigeminal neuralgia initially visited dental health professional for trigeminal-related facial pain. This finding indirectly indicate the level of miss diagnosis and delayed diagnosis our patients face currently in Ethiopia. Furthermore, this data indicate those patients who initially visited dental office for their facial pain were tends to be on higher dose of carbamazepine compared to those with out history of dental extraction. These findings were explained by the combined adverse effect of delayed diagnosis and extraction of healthy tooth resulted in requirement of higher dose of carbamazepine to control the facial pain. Thank you

本数据集源自一项基于医疗机构的横断面研究，旨在评估埃塞俄比亚亚的斯亚贝巴地区三叉神经痛（Trigeminal neuralgia, TN）患者的临床特征、治疗方案及相关影响因素。
本研究共纳入埃塞俄比亚亚的斯亚贝巴四家医疗机构的61例患者（n=61）。
所有在为期6个月的研究周期内前往这四家医疗机构就诊的确诊三叉神经痛患者均被纳入本研究。
所有患者均经持有执业资质的神经内科医师完成问诊与体格检查。
在获取所有患者的知情同意后，研究人员采用结构化问卷收集患者的人口学资料、临床资料及影像学数据。
本研究采用描述性分析、卡方检验、学生t检验、二元回归分析与多因素回归分析对研究结果进行阐释。
本数据集包含以下内容：人口学资料，以及与三叉神经痛相关的临床特征数据，具体包括疾病分型、病程时长、受累侧别、受累神经分支、拔牙史、疼痛性质、诱发因素、触发带、治疗满意度、用药类型及合并症情况。
此外还涵盖与相关自主神经功能障碍、三叉神经痛家族史、随季节波动的症状变化、手术史及脑部影像学表现相关的数据。
本数据集的数据均采集自神经内科门诊的横断面研究，因此分析与解读时需契合该研究的设计属性。
本研究团队决定与其他同行共享该数据集，因为这是埃塞俄比亚乃至撒哈拉以南非洲（sub-Saharan Africa, SSA）地区首项针对三叉神经痛的研究。
此前撒哈拉以南非洲地区关于三叉神经痛的临床资料极度匮乏，导致该地区三叉神经痛患者普遍存在诊疗不当、诊断延迟及治疗欠规范的问题。
截至目前，本研究是埃塞俄比亚首个三叉神经痛患者队列研究，因此本团队旨在明确该队列患者的临床特征，同时探究导致诊断延迟的原因及患者的治疗满意度情况。
本研究最重要的发现之一是，埃塞俄比亚三叉神经痛患者中拔牙史的患病率高达41%。该结果具有重要临床价值：近半数三叉神经痛患者最初因三叉神经相关的面部疼痛前往牙科医疗机构就诊，这一发现间接反映了当前埃塞俄比亚患者所面临的误诊与诊断延迟问题的严重程度。
此外，本数据集结果显示，最初因面部疼痛前往牙科就诊的患者，其服用的卡马西平剂量显著高于无拔牙史的患者。
上述结果可归因于诊断延迟与健康牙齿拔除的联合不良影响：这两种情况导致患者需要服用更高剂量的卡马西平才能有效控制面部疼痛。
特此致谢。