Potency of selected PDE inhibitors.
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https://figshare.com/articles/dataset/Potency_of_selected_PDE_inhibitors_/5411809
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From those compounds exhibiting IC50 <100 μM against recombinant GlPDE (aa588-1371) and EC50 <50 μM against Giardia trophozoites in the benchmark screening (see in Fig 3) exact dose responses were determined (values highlighted in green). PDE activity assays were done in triplicates and repeated at least once (SE of logIC50 < = 0.1), and Giardia cell susceptibility assays were done in quadruplicates and repeated 2 to 5 times (SE of logEC50 < = 0.15). n.d., not determined.
创建时间：
2017-09-27
