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资源简介：
Selected compounds that attenuate EBOVΔVP30.
应用场景：
创建时间：
2020-10-14
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Structurally Diverse Diterpenoids from Sandwithia guyanensis
Bioassay-guided fractionation of an EtOAc extract of the trunk bark of Sandwithia guyanensis, using a chikungunya virus (CHIKV)-cell-based assay, afforded 17 new diterpenoids 1–17 and the known jatroi
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DAS181 inhibits pandemic IFV A(H1N1): Viral Yield in MDCK culture (log10 infectious particles per 100 µl).
MDCK cells were pretreated with DAS181 for 2 hours (at indicated concentrations) before infection with A/Mexico/4604/2009, A/California/04/2009, or seasonal influenzas A/Hawaii/31/2007 or A/Hawaii/21/
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Inhibition of various RNA and DNA viruses by AT-511 compared to control compounds.
Inhibition of various RNA and DNA viruses by AT-511 compared to control compounds.
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Inhibition of SFV and SINV replication by selected hit compounds measured by CPE reduction and virus production assays.
aIC50 values against SFV and SINV were determined in dose-response experiments using an assay for the reduction of cytopathic effect. A concentration range from 200 µM to 0.1 µM was applied for each c
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IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infection
Background Ebolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical t
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