The final assessment of the optimal capture and detector Ig pairs with ranking according to their sensitivity derived from testing a clinical panel.

The data includes the epitopes recognized by the Igs where known, the LAM target(s) recognized by the pairs, the limit of detection to the Aoyama B strain cLAM (MTB Lineage 2) and the performance results after screening with a panel of 16 clinical specimens and a further 8 in the case of the top performing five Ig pairs. Key: Ig, antibody; Fab, antigen-binding fragment; MTX, 5-methylthio-xylofuranose; Ara, arabinose; Man, mannose; LAM, lipoarabinomannan; C, cultured LAM; U, urinary LAM; LoD, limit of detection; Sens., sensitivity; Spec., specificity.