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Induction of an Interferon Response Program in EGFR Mutant Lung Cancer by Tyrosine Kinase Inhibitors Positively Associates with Clinical Response

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE165019
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The goal of this study was to analyze rapid transcriptional responses induced by TKIs early in treatment that associate with the range of patient responses observed to oncogene specific inhibitors. RNA-seq was used to define transcriptional changes that occur in response to EGFR TKI in human lung cancer cell lines PC9, H1650, HCC4006, and H1975 and human 8 matched lung tumor biopsies.
创建时间:
2021-05-26
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