Induction of pluripotency in human cord blood unrestricted somatic stem cells

ChEBI2010-07-07 更新2026-07-21 收录

干细胞重编程

脐带血干细胞

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Induction of pluripotency in human cord blood unrestricted somatic stem cells

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2010-07-07

Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability

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The discovery that somatic cells are reprogrammable to pluripotency by ectopic expression of a small subset of transcription factors has created great potential for the development of broadly applicab

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Analysis of Differential Proteomes of Induced Pluripotent Stem Cells by Protein-Based Reprogramming of Fibroblasts

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The recent generation of induced pluripotent stem (iPS) cells represents a novel opportunity to complement embryonic stem (ES) cell-based approaches. iPS cells can be generated by viral transduction o

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Chemically reprogramming somatic cells to iPSCs is time-consuming and low-efficiency. Here, we discribe a rapid chemical reprogramming condition enabling generating iPSCs from MEFs in 12 days. To furt

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Reprogramming of mouse somatic cells into pluripotent stem cells using a combination of small molecules

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Somatic cells can be reprogrammed to generate induced pluripotent stem cells (iPSCs) by overexpression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc. Bmi1 is responsible for conversion o

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Epigenetic and transcriptional aberrations in human pluripotent stem cells reflect differences in reprogramming mechanisms [SNP array]

干细胞重编程

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Human pluripotent stem cells hold great potential for regenerative medicine, but available cell types have important limitations. While embryonic stem cells derived from fertilized embryos (IVF-ESCs)

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Induction of pluripotency in human cord blood unrestricted somatic stem cells

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