In Vivo Nanocapsule Characteristics and Information.

1Mean ± SD of the average elliptical diameter determined from TEM micrographs (magnification 230,000×) of 20 nanocapsules from two different grid preparations.2Average surface charge measured by DLS from two different preparations across a 20 volt potential in 1 mM KCl at 2 µg/ml. Data shown is the mean ± SE of 15 independent measurements.3Morphology of all nanocapsules determined by visual AFM and TEM observation as uniform, single capsules.4TBG-RNAi-CK2 encapsulation efficiency mean of 79.8±6.1% observed by Burton analysis relative to unencapsulated oligomer.5Upper case letters represent phosphodiester DNA bases; lower case letters represent 2′ O-methyl RNA bases.In Vivo Nanocapsule Characteristics and Information.