Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.

Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution. Descriptor: 1,2-ETHANEDIOL, 3-[(4-methylpiperazin-1-yl)methyl]-~{N}-[(4~{R})-4-methyl-2-pyrimidin-5-yl-3,4-dihydro-1~{H}-isoquinolin-7-yl]-5-(trifluoromethyl)benzamide, DI(HYDROXYETHYL)ETHER, ... Authors: Bartual, S.G, Pinkas, D.M, Wang, Z, Ding, K, Mahajan, P, Kupinska, K, Mukhopadhyay, S, Strain-Damerell, C, Chalk, R, Borkowska, O, Talon, R, Kopec, J, Williams, E, Tallant, C, Chaikuad, A, Sorell, F, Newman, J, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) Deposit date: 2015-12-16 Release date: 2016-10-26 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution. To Be Published

分辨率为2.65埃的DDR1受体酪氨酸激酶与D2164抑制剂复合物的晶体结构。组分信息：1,2-乙二醇、3-[(4-甲基哌嗪-1-基)甲基]-N-[(4R)-4-甲基-2-嘧啶-5-基-3,4-二氢-1H-异喹啉-7-基]-5-(三氟甲基)苯甲酰胺、二(羟乙基)醚等。作者：Bartual, S.G.、Pinkas, D.M.、Wang, Z.、Ding, K.、Mahajan, P.、Kupinska, K.、Mukhopadhyay, S.、Strain-Damerell, C.、Chalk, R.、Borkowska, O.、Talon, R.、Kopec, J.、Williams, E.、Tallant, C.、Chaikuad, A.、Sorell, F.、Newman, J.、Burgess-Brown, N.、von Delft, F.、Arrowsmith, C.H.、Edwards, A.M.、Bountra, C.、Bullock, A.；结构基因组学联盟（Structural Genomics Consortium, SGC）。提交日期：2015年12月16日，发布日期：2016年10月26日，最后修改日期：2024年10月9日。实验方法：X射线衍射（分辨率2.65埃）。引用说明：分辨率为2.65埃的DDR1受体酪氨酸激酶与D2164抑制剂复合物的晶体结构，待发表。