Total Synthesis of Aspeverin via an Iodine(III)-Mediated Oxidative Cyclization
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https://figshare.com/articles/dataset/Total_Synthesis_of_Aspeverin_via_an_Iodine_III_Mediated_Oxidative_Cyclization/2253829
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资源简介：
The
first total synthesis of aspeverin, a prenylated indole alkaloid
isolated from Aspergillus versicolor in 2013, is
described. Key steps utilized to assemble the core structure of the
target include a highly diastereoselective Diels–Alder reaction,
a Curtius rearrangement, and a unique strategy for installation of
the geminal dimethyl group. A novel iodine(III)-initiated cyclization
was then used to install the bicyclic urethane linkage distinctive
to the natural product.
创建时间：
2016-02-16
