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Morphological profiles of U-2 OS cells with cDNA-mediated overexpression

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Figshare2024-11-19 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Morphological_profiles_of_U-2_OS_cells_with_cDNA-mediated_overexpression/27854116
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Morphological profiles of U-2 OS cells perturbed with perturbations of cDNA-mediated overexpression. This is a re-processed version of data published in:Rohban, M. H., Singh, S., Wu, X., Berthet, J. B., Bray, M.-A., Shrestha, Y., Varelas, X., Boehm, J. S., & Carpenter, A. E. (2017). Systematic morphological profiling of human gene and allele function via Cell Painting. eLife, 6, e24060. https://doi.org/10/ghkrp7The data provided here has been reprocessed by combining data from the provided sqlite databases and csv files into a h5ad AnnData file, which can be read in with the AnnData Python package (documentation available here).Morphological profiles are present in the AnnData's X slot, other features that do not quantify a single cell's morphology directly are placed in obsm.Two versions of the data are available: the full data and a subsample in which only two DMSO wells and two C-EBP alpha wells were kept.Additionally, image-level data that can be used for quality control is provided, also as AnnData file.Lastly, for unit-testing, a small csv file is provided in the style of CellProfiler data exports. This file only contains data on four single-cells and is thus not meant for analysis purposes.The processing was performed by Jesko Wagner who claims no authorship of the data. The original data is distributed under CC0, which applies to this redistribution too.
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2024-11-19
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