首页/数据集/Echinococcus granulosus ubiquitin-conjugating enzymes (E2D2 and E2N) promote the formation of liver fibrosis in TGFβ1-induced LX-2 cells

Echinococcus granulosus ubiquitin-conjugating enzymes (E2D2 and E2N) promote the formation of liver fibrosis in TGFβ1-induced LX-2 cells

NIAID Data Ecosystem2026-05-01 收录

纤维化分子机制

寄生虫感染相关性肝病

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创建时间：

2023-09-27

纤维化分子机制

肝星状细胞激活

Hepatic fibrosis is a wound-healing response to chronic liver injury, which may result in cirrhosis and liver failure. The c-Jun N-terminal kinase-1 (JNK1) gene has been shown to be involved in liver

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Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products

纤维化分子机制

细胞-成纤维细胞互作

Methods: Two human lung primary fibroblast (HLF) lines were activated for 24 h with eosinophil conditioned media obtained from two blood eosinophil donors. Total RNA was extracted from HLF and treated

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ChIP-seq of HIF-1alpha and RNA-seq in kidney tubular cell line stimulated by hypoxia and TGF-beta. Homo sapiens

纤维化分子机制

转录调控

Hypoxia/HIF-1alpha pathway and TGF-beta/SMAD3 pathway have an essential role in the progression of kidney injury, but their interaction and its effect on transcriptional regulation is not fully unders

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Chitinase-3 Like 1 Is a Profibrogenic Factor Overexpressed in Aging Livers and in Patients with Cirrhosis in the Aging Liver and in Patients with Liver Cirrhosis

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衰老相关基因表达

Older age at the time of infection with hepatitis viruses is associated with an increased risk of liver fibrosis progression, but the mechanisms remain unclear. We hypothesized that the pace of liver

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Additional file 14: Table S7. of A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

HBV相关肝癌

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HBV integration sites identified in BGI, TCGA, and ICGC cohorts. (XLSX 92 kb)

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