Effect of Corexit alone and in combination with DWH mousse upon the incidence of zebrafish embryo developmental abnormalities: Direct contact and non-contact exposures to mousse

Dataset examines the developmental abnormalities of DWH mousse and Corexit in a dispersant dose response experimental design. This study shows that Corexit elicited no added developmental toxicity as compared to controls (no Corexit: no mousse). The mousse on the other hand clearly elicited developmental toxicity in embryos exposed to mousse both by direct contact and non-contact exposures. Direct contact exposures as found with substrate breeding fishes was more effective in eliciting developmental toxicity from DWH mousse than non-contact waterborne exposures. This direct contact response was a largely independent of Corexit concentration except at the highest Corexit concentration. Corexit on the other hand influenced the incidence of abnormalities for non-contact exposures.本数据集采用分散剂剂量反应实验设计，探究了DWH泡沫（DWH mousse）与柯塞克斯（Corexit）引发的发育异常情况。本研究结果显示，与对照组（无柯塞克斯且无泡沫组）相比，柯塞克斯未引发额外的发育毒性。与之相对，泡沫可在通过直接接触与非接触方式暴露于该泡沫的胚胎中，显著诱发发育异常。相较于非接触水媒暴露，在底栖产卵鱼类中观测到的直接接触暴露方式，更易由DWH泡沫引发发育毒性。除最高浓度的柯塞克斯组外，这种直接接触引发的毒性响应基本不受柯塞克斯浓度的影响。而柯塞克斯则会对非接触暴露情况下的发育异常发生率产生影响。