Elecsys Syphilis Signal-to-Cutoff

Supplementary file 1: Data for 19,368 syphilis screening tests on 15,764 unique patients using the Roche Diagnostics Elecsys Syphilis assay. All laboratory data involve analysis on plasma or serum. Specific data fields include: unique patient identification number (deidentified), whether result was first or only syphilis screening test performed for the specific patient within the retrospective timeframe or a repeat test (with days after initial test recorded), age in years, sex (as recorded in the electronic medical record), clinical location/unit at time of testing (emergency department, infectious disease clinic, obstetrics, inpatient, or outpatient clinic other than infectious diseases or obstetrics), syphilis screening result (negative or positive), and S/CO value for the syphilis screening.

Supplementary file 2: Data for 355 positive syphilis screening tests on 270 unique patients using the Roche Diagnostics Elecsys Syphilis assay. All laboratory data involve analysis on plasma or serum. Specific data fields include: unique patient identification number (deidentified), whether result was first or only syphilis screening test performed for the specific patient within the retrospective timeframe or a repeat test, age in years, sex (as recorded in the electronic medical record), clinical location/unit at the time of syphilis testing (emergency department, infectious disease clinic, obstetrics, inpatient, or outpatient), S/CO value, results of subsequent testing in the reverse algorithm cascade (classified into the following categories: RPR reactive with specific titer noted, RPR and TP-PA non-reactive, RPR non-reactive / TP-PA inconclusive, and RPR non-reactive / TP-PA reactive), specific category (including RPR reactive results broken down into 1:1 to 1:8 and 1:16 or higher subgroups), and clinical notes.