Additional file 1: of Increased PHGDH expression promotes aberrant melanin accumulation
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Figure S1. Generation of the PHGDHtetO allele. Figure S2. Tissues from mice with long-term exposure to doxycycline diet show variable PHGDH expression. Figure S3. PHGDH expression leads to melanin accumulation in early anagen hair follicles but does not globally affect timing of the hair follicle cycle. Figure S4. Validation of species-specific PHGDH qPCR primers. Figure S5. Evidence that adipocytes and keratinocytes sort into the GFP- fraction when cells are isolated from the skin of PHGDHtetO; Dct-rtTA; H2B-GFPtetO mice. Supplementary methods. (ZIP 1160 kb)
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figshare
创建时间:
2019-07-23



