Clinical and biochemical characteristics of COVID(+) and COVID(-) patients with hyperglycemic crisis: a cross-sectional study

A cross-sectional study was conducted with 82 patients admitted to an urban academic medical center in Philadelphia, PA, USA between March 1^st and July 30^th, 2020. Data were collected by computer query and manual review of electronic health records. Patients met lab criteria for either DKA (serum bicarbonate ≤18 mEq/L, anion gap >10, ketonemia or ketonuria, and arterial pH ≤7.30), or HHS (blood glucose > 33.3 mmol/L and osmolality > 320 mOsm/kg).[7] Mixed DKA-HHS was defined as meeting all criteria for either DKA or HHS with at least 1 criterion for the other diagnosis. Diagnoses were adjudicated by an endocrinologist.