Hydrocortisone (HC) and triiodothyronine (T3) have both been shown to be capable of independently inhibiting hyaluronate (HA, hyaluronic acid) synthesis in a self-assembled human dermal equivalent (hu
There is a need to develop economical, efficient and widely available therapeutic approaches to enhance the rate of skin wound healing. The optimal outcome of wound healing is restoration to the pre-w
We have prepared tissue engineered self assembled dermal equivalents with high similarity to the human dermis (skin). Overall design: We have manipulated the culture conditions to prepare dermal equiv
Characterize reconstructed human skin (RhS) models metabolically and investigate the role of adipose tissue in skin metabolism. Overall design: RNA-sequencing to compare expression profiles of RhS and
