JAAD-D-19-02716 Supplemental materials

Supplementary materials for publication JAAD-D-19-02716 (Lim et al. Novel Mutations Identified by Whole Exome Sequencing in Acral Melanoma. J Am Acad Dermatol. 2020) Supplementary Appendix 1: Detailed methods Supplementary Appendix 2: Clinical details of 31 acral melanoma patients including 7 nail apparatus melanoma patients Supplementary Appendix 3: Single nucleotide variations and small indels identified through WES Supplementary Appendix 4: Several genes whose mutations were repeatedly detected in this study and previously reported in the literature in association with melanoma Supplementary Appendix 5: Previous studies on the association of CSMD3 and EHMT1 with malignancies期刊论文JAAD-D-19-02716的补充材料（Lim等人，《通过全外显子组测序（Whole Exome Sequencing）识别肢端黑色素瘤中的新型突变》，发表于《美国皮肤病学会杂志》2020年） 补充附录1：详细实验方法 补充附录2：31例肢端黑色素瘤患者的临床详情，其中包含7例甲下黑色素瘤患者 补充附录3：通过全外显子组测序（Whole Exome Sequencing，WES）鉴定得到的单核苷酸变异与小插入缺失变异 补充附录4：本研究中反复检出突变、且既往文献中报道与黑色素瘤相关的若干基因 补充附录5：关于CSMD3及EHMT1与恶性肿瘤关联的既往研究