On the utility of Cas13d for genetic interaction mapping

NIAID Data Ecosystem2026-05-01 收录

基因敲低实验

遗传相互作用

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https://zenodo.org/record/10868765 数据链接链接失效反馈

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Scripts to calculate tau values and genetic interaction (GI) scores in knockdown experiments using Cas13d.

创建时间：

2024-03-28

A Large-Scale Complex Haploinsufficiency-Based Genetic Interaction Screen in Candida albicans : Analysis of the RAM Network during Morphogenesis

真菌形态发生

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The morphogenetic transition between yeast and filamentous forms of the human fungal pathogen Candida albicans is regulated by a variety of signaling pathways. How these pathways interact to orchestra

NIAID Data Ecosystem70

Supplementary Table 6 from Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities

RAS信号通路

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Results from the "GI-Directed" sublibrary screen. Different metrics are reported on each of the three tabs of the spreadsheet as indicated. GI-T-Score : GIT Score; MWU Adj Pval: FDR of Mann-Whitney U

NIAID Data Ecosystem60

MDM33 overexpression suppressor screen. Saccharomyces cerevisiae

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基因功能

We performed a genome-wide screen for genetic MDM33 interaction partners. Using the opposite approach of the well known synthetic dosage lethality (screening for deletion strains in which a non-toxic

NIAID Data Ecosystem50

Additional file 4 of A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens

CRISPRi筛选

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Supplementary Material 4

DataCite Commons2024-08-16 更新70

Knock down of C11orf67 by shRNA in SUM52PE

基因敲低实验

基因表达调控

SUM52PE cells were lentivirally transduced with PKLO empty vector control (Sigma SHC001 MISSION PLKO.1-PURO CONTROL VECTOR) or shRNA specific for C11orf67 (Sigma Clone ID: NM_024684.2-280s21c1 SHCLND-

NIAID Data Ecosystem50

On the utility of Cas13d for genetic interaction mapping

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